IGE ANTIBODY-RESPONSE TO MITE ANTIGENS IN MITE INFESTED MICE

被引:24
作者
LALTOO, H
VANZOOST, T
KIND, LS
机构
[1] Department of Microbiology, Faculty of Medicine, Dalhousie University, Halifax, NS
来源
IMMUNOLOGICAL COMMUNICATIONS | 1979年 / 8卷 / 01期
关键词
D O I
10.3109/08820137909044702
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Mice infested at birth with the mouse mite Myocoptes musculinus developed positive skin tests to mite antigens at the age of 5 weeks. Serum IgE antibodies directed against mite antigens were first detected at 6 weeks of age and high levels of IgE were present as long as 1 year later. Similar kinetics of IgE formation were observed in mice infested as adults. Mast cell degranulation by mite extract was demonstrated in connective tissue obtained from the skin of mite infested mice. © 1979 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:1 / 9
页数:9
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