CONTROL FACTORS OF GRANULOPOIESIS IN HUMAN-SERUM

被引：13

作者：

BOLIN, RW ^{[1
]}

ROBINSON, WA ^{[1
]}

机构：

[1] UNIV COLORADO, MED CTR, DEPT MED, ONCOL SECT, DENVER, CO 80262 USA

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 1979年 / 6卷 / 01期

关键词：

CSA; granulopoiesis; regulation; serum;

D O I：

10.1002/ajh.2830060102

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The role of serum factors in the modulation of production of colony‐stimulating activity (CSA) has been investigated. A factor has been described, and partially characterized, in human serum that has the capacity to stimulate increased synthesis and release of CSA by human mononuclear cells (MNC). MNC RNA and protein synthesis are required to demonstrate this effect of serum, but DNA synthesis and mitotic division are not required. The factor in serum resulting in this effect is a heat‐labile protein with a molecular weight slightly greater than that of CSA. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：1 / 10

页数：10

共 22 条

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