SYNTHESIS OF ALKYL NITRONATES VIA MITSUNOBU CONDENSATION

被引：21

作者：

FALCK, JR ^{[1
]}

YU, JR ^{[1
]}

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT PHARMACOL,DALLAS,TX 75235

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 45期

基金：

美国国家卫生研究院;

关键词：

NITRONATE; NITRONIC ESTER; MITSUNOBU; 2-ISOXAZOLINE-2-OXIDE; 5,6-DIHYDRO-4H-OXAZINE-2-OXIDE;

D O I：

10.1016/S0040-4039(00)61760-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitroalkanes bearing electron-withdrawing or unsaturated substituents at the alpha-carbon experience exclusive intra- and intermolecular 0-alkylation by alcohols under Mitsunobu condensation conditions furnishing good to excellent yields of alkyl nitronates; in contrast, 1-phenylsulphonyl-1-nitro-3-propanol affords mainly the corresponding cyclopropane.

引用

页码：6723 / 6726

页数：4

共 18 条

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