THE PECULIAR JOURNEY OF A SELFISH CHROMOSOME - MOUSE T-HAPLOTYPES AND MEIOTIC DRIVE

被引：208

作者：

SILVER, LM

机构：

[1] Department of Molecular Biology, Princeton University, Princeton

来源：

TRENDS IN GENETICS | 1993年 / 9卷 / 07期

关键词：

D O I：

10.1016/0168-9525(93)90090-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Mouse t haplotypes are descendents of a variant form of chromosome 17 that evolved the ability to propagate itself at the expense of the wild-type homolog from heterozygous +/t males. Although once enigmatic, these widespread selfish chromosomes have revealed many of their secrets in response to a combined assault with molecular, genetic and phylogenetic techniques. This review summarizes the current understanding of t haplotypes and their raison d'etre.

引用

页码：250 / 254

页数：5

共 36 条

[1] GENE-MAPPING WITHIN THE T/T COMPLEX OF THE MOUSE .1. TERT-LETHAL GENES ARE NONALLELIC [J].