METHOD FOR THE DYNAMIC CONTINUOUS ESTIMATION OF EXCITABILITY CHANGES OF SINGLE FIBER TERMINALS IN THE CENTRAL NERVOUS-SYSTEM

被引：29

作者：

MADRID, J ^{[1
]}

ALVARADO, J ^{[1
]}

DUTTON, H ^{[1
]}

RUDOMIN, P ^{[1
]}

机构：

[1] POLITEC NACL,CTR INVEST,DEPT PHYSIOL & BIOPHYS,MEXICO CITY,MEXICO

来源：

NEUROSCIENCE LETTERS | 1979年 / 11卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0304-3940(79)90003-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A method is presented allowing direct and continuous estimation of the excitability changes of single fiber terminal arborizations within the central nervous system. In essence, the method measures the current required to maintain a preset antidronic firing probability of the unit under study. This implies operation in a closed loop system controlled by a computer. With this technique one can accurately determine input-output curves of single units requiring relatively small current variations (0.15-2.1 μA) to change from zero to maximal probability of response. The method also allows measurement of the excitability changes produced by conditioning volleys to sensory nerves. © 1979.

引用

页码：253 / 258

页数：6

共 7 条

[1]

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[5] EFFECTS OF MUSCLE AND CUTANEOUS AFFERENT NERVE VOLLEYS ON EXCITABILITY FLUCTUATIONS OF IA TERMINALS [J].

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[6]

WALL PD, 1958, J PHYSIOL-LONDON, V142, P1

[7] EXCITABILITY CHANGES OF TERMINAL ARBORIZATIONS OF SINGLE IA AND IB AFFERENT-FIBERS PRODUCED BY MUSCLE AND CUTANEOUS CONDITIONING VOLLEYS [J].

WILLIS, WD ;

NUNEZ, R ;

RUDOMIN, P .

JOURNAL OF NEUROPHYSIOLOGY, 1976, 39 (06) :1150-1159

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