GENETIC-VARIATION IN MOUSE SALIVARY AMYLASE RATE OF SYNTHESIS

被引:44
作者
HJORTH, JP
机构
[1] Institute of Ecology and Genetics, University of Aarhus, Aarhus C
关键词
genetic variation; Mus musculus; rate of synthesis; salivary amylase;
D O I
10.1007/BF00502125
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Heterozygotes from matings of the mouse strains YBR/Cv and C3H/As have about 3 times more YBR-amylase than C3H-amylase in the saliva. The determinant for this quantitative effect is located on linkage group XVI close to or within the structural gene for salivary amylase. The quantitative effect is the result of an increase in the rate of synthesis of YBR-amylase, and the determinant is cis acting. Studies of other mouse strains suggest that regulatory genetic elements may modulate salivary amylase production. © 1979 Plenum Publishing Corporation.
引用
收藏
页码:665 / 682
页数:18
相关论文
共 26 条
[1]  
BREEN GAM, 1977, GENETICS, V85, P73
[2]  
CHAPMAN VM, 1979, INBRED GENETICALLY D, P77
[3]  
CHOVNICK A, 1976, GENETICS, V84, P233
[4]   SIMPLIFIED DISC ( POLYACRYLAMIDE GEL ) ELECTROPHORESIS [J].
CLARKE, JT .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1964, 121 (A2) :428-&
[6]  
DOYLE D, 1969, J BIOL CHEM, V244, P5449
[7]  
EICHER EM, 1976, MOUSE NEWS LETT, V54, P41
[8]  
HANFORD WC, 1977, J BIOL CHEM, V252, P6695
[9]  
HJORTH JP, BIOCH GENET
[10]  
HJORTH JP, GENETICS