REGULATORY LOCUS FOR MOUSE BETA-GLUCURONIDASE INDUCTION, GUR, CONTROLS MESSENGER-RNA ACTIVITY

被引：50

作者：

PAIGEN, K

LABARCA, C

WATSON, G

机构：

[1] Department of Molecular Biology, Roswell Park Memorial Institute, Buffalo

来源：

SCIENCE | 1979年 / 203卷 / 4380期

关键词：

D O I：

10.1126/science.760204

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A regulatory locus in a higher organism has been shown to control a specific messenger RNA activity. The Gur locus in mice regulates the production of kidney β-glucuronidase messenger RNA activity after induction of the β-glucuronidase structural gene, Gus, by testosterone. β-Glucuronidase messenger RNA was assayed by its ability to direct the synthesis of catalytically active murine β-glucuronidase in Xenopus oocytes. Copyright © 1979 AAAS.

引用

页码：554 / 556

页数：3

共 17 条

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