EFFECT OF DILTIAZEM, NIFEDIPINE AND VERAPAMIL ON THE ANTINOCICEPTIVE ACTION OF ACETYLSALICYLIC-ACID IN MICE

被引：12

作者：

ALHUMAYYD, MS

机构：

[1] Department of Medical Pharmacology, College of Medicine, King Saud University, Riyadh

来源：

GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM | 1991年 / 22卷 / 01期

关键词：

D O I：

10.1016/0306-3623(91)90321-V

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. Diltiazem, verapamil and nifedipine produced a dose-dependent analgesic response in mice. 2. A fixed oral dose of acetylsalicylcic acid increased this analgesic response. 3. Analgesia was maintained when mice were treated chronically with calcium channel blockers alone or when combined with aspirin.

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页码：121 / 125

页数：5

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