ASSESSMENT OF THE SENSITIVITY OF BIOIMPEDANCE TO VOLUME CHANGES IN BODY-WATER

被引：17

作者：

BRADBURY, MG

SMYE, SW

BROCKLEBANK, JT

机构：

[1] Academic Unit of Paediatrics and Child Health, St. James's University Hospital, Leeds

[2] Department of Medical Physics, St. James's University Hospital, Leeds

来源：

PEDIATRIC NEPHROLOGY | 1995年 / 9卷 / 03期

关键词：

ELECTRICAL IMPEDANCE; HEMODIALYSIS; TOTAL BODY WATER; ULTRAFILTRATION;

D O I：

10.1007/BF02254204

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The sensitivity of whole-body electrical impedance measurements to changes in the volume of total body water in 12 children undergoing haemodialysis has been assessed. The impedance (I) of each child was measured at 20-min intervals during dialysis using the standard four-electrode technique to apply a constant current (800 mu A, 50 kHz) between the wrist and ankle on the non-fistula side of the patient. The ultrafiltration volume (U) was also recorded. A simple electrical model suggests that U = aHt(2) ((1/I-o)-(1/I)), where I-o is the whole body impedance at the start of dialysis, a is a constant and Ht is patient height. No significant changes in I were measured on 4 patients undergoing dialysis without ultrafiltration, whereas in 8 patients undergoing ultrafiltration and dialysis I increased. Linear regression analysis and the above equation gave a mean value for a = 0.566 1 Ohm/cm(2) (coefficient of variation = 3%), (mean r = 0.97), values comparable to those values obtained from isotope dilution studies. Predicted fluid loss in 8 patients following a single dialysis session gave a mean overestimate of 4.3% (limits of agreement 27.3% and -19.7%), although in 6 of the patients agreement was to within 6%. Changes in impedance reflect changes in total body water in children undergoing haemodialysis and are relatively insensitive to factors such as the possible differences in electrolyte levels between these patients.

引用

页码：337 / 340

页数：4

共 16 条

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