CARDIOTOXICITY OF NAJA-NIGRICOLLIS PHOSPHOLIPASE-A2 IS NOT DUE TO ALTERATIONS IN PROSTAGLANDIN SYNTHESIS

被引：12

作者：

BARRINGTON, PL ^{[1
]}

SOONS, KR ^{[1
]}

ROSENBERG, P ^{[1
]}

机构：

[1] UNIV CONNECTICUT,SCH PHARM,PHARMACOL & TOXICOL SECT,STORRS,CT 06268

来源：

TOXICON | 1986年 / 24卷 / 11-12期

关键词：

D O I：

10.1016/0041-0101(86)90137-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1107 / 1116

页数：10

共 42 条

[1] SYNTHESIS OF PROSTAGLANDINS BY CULTURED RAT-HEART MYOCYTES AND CARDIAC MESENCHYMAL CELLS [J].

AHUMADA, GG ;

SOBEL, BE ;

NEEDLEMAN, P .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1980, 12 (07) :685-700

[2]

ANSELL GB, 1973, FORM FUNCTION PHOSPH, V3

[3] DEVELOPMENTAL ALTERATIONS IN 5'-NUCLEOTIDASE KINETICS AND LIPID-COMPOSITION OF RAT-HEART SARCOLEMMA [J].

AWAD, AB ;

CHATTOPADHYAY, JP .

MECHANISMS OF AGEING AND DEVELOPMENT, 1983, 22 (02) :151-158

[4] CARDIOTOXIC EFFECTS OF NAJA-NIGRICOLLIS VENOM PHOSPHOLIPASE-A2 ARE NOT DUE TO PHOSPHOLIPID HYDROLYTIC PRODUCTS [J].

BARRINGTON, PL ;

YANG, CC ;

ROSENBERG, P .

LIFE SCIENCES, 1984, 35 (09) :987-995

[5] EFFECT OF CARBOXYLATE GROUP MODIFICATION ON ENZYMATIC AND CARDIOTOXIC PROPERTIES OF SNAKE-VENOM PHOSPHOLIPASES-A-2 [J].

BARRINGTON, PL ;

CONDREA, E ;

SOONS, KR ;

YANG, CC ;

ROSENBERG, P .

TOXICON, 1984, 22 (05) :743-758

[6]

BARTLETT GR, 1959, J BIOL CHEM, V234, P466

[7] PROSTAGLANDIN SYNTHESIS BY ADULT HEART MYOCYTES [J].

BOLTON, HS ;

CHANDEBHAN, R ;

BRYANT, RW ;

BAILEY, JM ;

WEGLICKI, WB ;

VAHOUNY, GV .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1980, 12 (11) :1287-1298

[8] DEMONSTRATION OF PHOSPHOLIPID SPLITTING AS FACTOR RESPONSIBLE FOR INCREASED PERMEABILITY AND BLOCK OF AXONAL CONDUCTION INDUCED BY SNAKE VENOM [J].

CONDREA, E ;

ROSENBER.P ;

DETTBARN, WD .

BIOCHIMICA ET BIOPHYSICA ACTA, 1967, 135 (04) :669-+

[9] COMPARISON OF A RELATIVELY TOXIC PHOSPHOLIPASE-A2 FROM NAJA-NIGRICOLLIS SNAKE-VENOM WITH THAT OF A RELATIVELY NON-TOXIC PHOSPHOLIPASE-A2 FROM HEMACHATUS-HAEMACHATUS SNAKE-VENOM .1. ENZYMATIC-ACTIVITY ON FREE AND MEMBRANE-BOUND SUBSTRATES [J].

CONDREA, E ;

YANG, CC ;

ROSENBERG, P .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (11) :1555-1563

[10] DISSOCIATION OF ENZYMATIC-ACTIVITY FROM LETHALITY AND PHARMACOLOGICAL PROPERTIES BY CARBAMYLATION OF LYSINES IN NAJA-NIGRICOLLIS AND NAJA-NAJA-ATRA SNAKE-VENOM PHOSPHOLIPASES A2 [J].

CONDREA, E ;

FLETCHER, JE ;

RAPUANO, BE ;

YANG, CC ;

ROSENBERG, P .

TOXICON, 1981, 19 (05) :705-720

← 1 2 3 4 5 →