INDUCTION OF MICRONUCLEATED RETICULOCYTES BY POTASSIUM BROMATE AND POTASSIUM CHROMATE IN CD-1 MALE-MICE

被引：18

作者：

AWOGI, T

MURATA, K

UEJIMA, M

KUWAHARA, T

ASANAMI, S

SHIMONO, K

MORITA, T

机构：

[1] KUMIAI CHEM IND CO LTD, KIKUGAWA, SHIZUOKA 439, JAPAN

[2] OTSUKA PHARMACEUT FACTORY INC, TOKUSHIMA 772, JAPAN

[3] NIPPON GLAXO LTD, NERIMA KU, TOKYO 177, JAPAN

来源：

MUTATION RESEARCH | 1992年 / 278卷 / 2-3期

关键词：

MICRONUCLEUS TEST; PERIPHERAL BLOOD RETICULOCYTES; ACRIDINE ORANGE; SUPRAVITAL STAINING; KBRO3; K2CRO4;

D O I：

10.1016/0165-1218(92)90231-N

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Micronucleus tests of potassium bromate (KBrO3) and potassium chromate (K2CrO4) were conducted with peripheral blood reticulocytes (PB-RETs) of CD-1 male mice dosed intraperitoneally. Peripheral blood cells collected from the tail were stained supravitally with acridine orange (AO) using AO-coated glass slides. Both KBrO3 and K2CrO4 induced micronuclei in PB-RETs in the same manner as in polychromatic erythrocytes of bone marrow.

引用

页码：181 / 185

页数：5

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