AIRWAY RESPONSE TO HAIR SPRAY IN NORMAL SUBJECTS AND SUBJECTS WITH HYPERREACTIVE AIRWAYS

被引:20
作者
SCHLUETER, DP [1 ]
SOTO, RJ [1 ]
BARETTA, ED [1 ]
HERRMANN, AA [1 ]
OSTRANDER, LE [1 ]
STEWART, RD [1 ]
机构
[1] MED COLL WISCONSIN,DEPT ENVIRONM MED,MILWAUKEE,WI 53226
关键词
D O I
10.1378/chest.75.5.544
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Short-term 20-second exposure to hair sprays A and B failed to show significant decreases in maximum expiratory flow rates at low pulmonary volumes in normal subjects; however, significant decreases were observed with hair spray B in eight subjects with hyperreactive airways (abnormal response to inhalation of methacholine). On the partial flow-volume curves, flows at 40 percent and 25 percent of forced vital capacity decreased 8.9 to 10.3 percent and 14 to 18.7 percent, respectively. The hair sprays differed in their content of perfume and plasticizer, and since the latter is generally considered nontoxic at room temperature, the perfume may be the responsible agent. It would appear from this study that normal healthy individuals are at little risk, at least from brief exposure to hair spray; however, in the presence of hyperreactive airways, as seen in asthmatic subjects and in some people with allergic rhinitis and viral respiratory infections, an immediate response of the airways may result from exposure to some hair sprays.
引用
收藏
页码:544 / 548
页数:5
相关论文
共 20 条
[1]   THESAUROSIS FOLLOWING INHALATION OF HAIR SPRAY - CLINICAL AND EXPERIMENTAL STUDY [J].
BERGMANN, M ;
FLANCE, IJ ;
BLUMENTHAL, HT .
NEW ENGLAND JOURNAL OF MEDICINE, 1958, 258 (10) :471-476
[2]   THESAUROSIS DUE TO INHALATION OF HAIR SPRAY - REPORT OF 12 NEW CASES, INDLUDING 3 AUTOPSIES [J].
BERGMANN, M ;
ARONSON, PR ;
CRUZ, PT ;
KLAM, N ;
FLANCE, IJ ;
JOSHI, RA ;
BLUMENTHAL, HT .
NEW ENGLAND JOURNAL OF MEDICINE, 1962, 266 (15) :750-&
[3]   MAXIMUM EXPIRATORY FLOW RATES IN INDUCED BRONCHOCONSTRICTION IN MAN [J].
BOUHUYS, A ;
HUNT, VR ;
KIM, BM ;
ZAPLETAL, A .
JOURNAL OF CLINICAL INVESTIGATION, 1969, 48 (06) :1159-&
[4]  
BOUHUYS A, 1970, AIRWAY DYNAMICS PHYS, P263
[5]   AIRWAY RESPONSES TO INHALED HISTAMINE IN ASYMPTOMATIC SMOKERS AND NONSMOKERS [J].
BROWN, NE ;
MCFADDEN, ER ;
INGRAM, RH .
JOURNAL OF APPLIED PHYSIOLOGY, 1977, 42 (04) :508-513
[6]   PERIPHERAL AIRWAY RESPONSES TO ACUTE HAIR-SPRAY EXPOSURE [J].
COHEN, BM .
RESPIRATION, 1977, 34 (05) :270-277
[7]   PULMONARY-DISEASE ASSOCIATED WITH INHALATION OF COSMETIC AEROSOLS [J].
EHRHARDT, DR ;
AHN, C ;
SAWYERS, TM .
CHEST, 1973, 64 (02) :251-254
[8]  
EMPEY DW, 1976, AM REV RESPIR DIS, V113, P131
[9]   PULMONARY INFILTRATION DUE TO AEROSOL THESAUROSIS [J].
GOWDY, JM ;
WAGSTAFF, MJ .
ARCHIVES OF ENVIRONMENTAL HEALTH, 1972, 25 (02) :101-&
[10]   TIME-DEPENDENCE OF FLOW-VOLUME CURVES [J].
GREEN, M ;
MEAD, J .
JOURNAL OF APPLIED PHYSIOLOGY, 1974, 37 (06) :793-797