LIGHT-INDUCED PLASMA MELATONIN SUPPRESSION IN SEASONAL AFFECTIVE-DISORDER

被引：5

作者：

GADDY, JR

STEWART, KT

BYRNE, B

DOGHRAMJI, K

ROLLAG, MD

BRAINARD, GC

机构：

[1] THOMAS JEFFERSON UNIV,JEFFERSON MED COLL,DEPT NEUROL,PHILADELPHIA,PA 19107

[2] UNIFORMED SERV UNIV HLTH SCI,DEPT ANAT,BETHESDA,MD 20814

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 1990年 / 14卷 / 04期

关键词：

light; light sensitivity; melatonin; melatonin suppression; seasonal affective disorder;

D O I：

10.1016/0278-5846(90)90007-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

1. Subjects with seasonal afffective disorder were exposed to 0, 500 and 1000 lux of white light for one hour beginning at 0300 hours. 2. Plasma samples were taken periodically and analysed for melatonin. 3. Plasma melatonin levels were suppressed by exposure to both 500 and 1000 lux light levels, suggesting that SAD patients show no neuroendocrine insensitivity to light but may show supersensitive responses to light. © 1990.

引用

页码：563 / 568

页数：6

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