ANTI-REMODELING EFFECTS OF ACE-INHIBITORS

被引：3

作者：

MCDONALD, KM

机构：

[1] Cardiovascular Division, Univ. of Minnesota Medical School, Box 508 UMHC, Minneapolis, MN 55455

来源：

CORONARY ARTERY DISEASE | 1995年 / 6卷 / 04期

关键词：

ANGIOTENSIN CONVERTING ENZYME INHIBITORS; VENTRICULAR REMODELING; MYOCARDIAL INFARCTION; LEFT VENTRICULAR DYSFUNCTION;

D O I：

10.1097/00019501-199504000-00005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Extensive experimental and clinical work has demonstrated the prognostic importance of ventricular remodeling following myocardial infarction. Indeed these structural changes may represent one of the more important prognostic determinants of outcome in this setting. Significant advances have been made in the pharmacologic attenuation of remodeling specifically through the use of ACE inhibitor therapy. Ongoing and future studies should provide clinical information on the mechanisms initiating the remodeling process and thereby allow the development of even more effective therapeutic strategies to attenuate this process.

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页码：295 / 301

页数：7

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