THE HAZARDS OF CHLOROQUINE SELF PRESCRIPTION IN WEST-AFRICA

被引：17

作者：

DEMAZIERE, J ^{[1
]}

FOURCADE, JMN ^{[1
]}

BUSSEUIL, CTA ^{[1
]}

ADELEINE, P ^{[1
]}

MEYER, SM ^{[1
]}

SAISSY, JM ^{[1
]}

机构：

[1] HOP PRINCIPAL,DAKAR,SENEGAL

来源：

JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY | 1995年 / 33卷 / 04期

关键词：

ACCIDENTAL POISONING; ACUTE CHLOROQUINE POISONING; POISONING IN AFRICA; TORSADES DE POINTES;

D O I：

10.3109/15563659509028925

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

We report a severe accidental chloroquine poisoning in a West African adult. This intoxication results from the widespread practice in Senegal of taking mild doses of chloroquine for a few days (i.e. 300 mg x 3 for 3 or 5 days)following the onset of any fever suspected of being a malaria attack. To our knowledge, this practice and this kind of poisoning have not been reported before. The present clinical case demonstrated that self-medication can be the cause of severe chloroquine poisoning responsible for arrhythmia (torsades de pointes). In this clinical case, no diazepam was administered. However, there were no further problems and the patient was discharged three days after admission to the intensive care unit.

引用

页码：369 / 370

页数：2

共 6 条

[1]

CARSON JW, 1967, PEDIATRICS, V40, P449

[2] CHLOROQUINE POISONING - VENTRICULAR-FIBRILLATION FOLLOWING TRIVIAL OVERDOSE IN A CHILD [J].