LOSS OF H-2KK GENE PRODUCT(S) FROM AN AKR SPONTANEOUS LEUKEMIA

被引:77
作者
SCHMIDT, W
ATFIELD, G
FESTENSTEIN, H
机构
[1] Department of Immunology, London Hospital Medical College, London, E1 2AD, Turner Street
关键词
D O I
10.1007/BF01561442
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Serological absorption analyses and immunochemical studies of the H-2 antigenic specificities on the AKR (H-2k) spontaneous leukaemia K36 have been performed. The results confirm the absence of the H-2Kk gene product from the cell surface and from detergent solubilised tumour cells. A genetic mechanism is considered for this phenotypic alteration. © 1979 Springer-Verlag New York Inc.
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页码:311 / 321
页数:11
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