ARACHIDONIC-ACID METABOLISM IN HUMAN AND BOVINE RETINA

被引：10

作者：

KULKARNI, PS

机构：

[1] Department of Ophthalmology and Visual Science, Kentucky Lions Eye Research Institute, University of Louisville School of Medicine, Louisville, Kentucky

来源：

JOURNAL OF OCULAR PHARMACOLOGY | 1991年 / 7卷 / 02期

关键词：

D O I：

10.1089/jop.1991.7.135

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Arachidonic acid (AA) metabolism in the human and bovine retina was assessed. This study demonstrates that the human and bovine retina can synthesize prostaglandin (PG) E2, F2-alpha, I2, D2 and thromboxane A2 from C-14-AA. This tissue also synthesized leukotriene (LT) B4 and 12-hydroxyeicosatetraenoic acid (12-HETE). Although human and bovine retina metabolized AA into PGs and LTs, the ability to synthesize these products was considerably less than some other ocular tissues of various species.

引用

页码：135 / 139

页数：5

共 15 条

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