A SIMPLE METHOD FOR INTRODUCING - SH/COOH GROUP AT 5'-OH END OF OLIGONUCLEOTIDE

被引：12

作者：

KUMAR, A

ADVANI, S

机构：

[1] National Institute Of Immunology, Shahid Jeet Singh Marg, New Delhi

来源：

NUCLEOSIDES & NUCLEOTIDES | 1992年 / 11卷 / 05期

关键词：

D O I：

10.1080/07328319208021163

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A method for introducing a -SH group at the 5'-end of the oligonucleotide using S-Trityl-L-Cysteine has been developed. Carbonyl diimidazole was used for activating the 5'-OH group.

引用

页码：999 / 1002

页数：4

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