SYNTHESIS OF SUITABLY-PROTECTED PHOSPHORAMIDITES OF 2'-FLUORO-2'-DEOXYGUANOSINE AND 2'-AMINO-2'-DEOXYGUANOSINE FOR INCORPORATION INTO OLIGORIBONUCLEOTIDES

被引：20

作者：

BENSELER, F ^{[1
]}

WILLIAMS, DM ^{[1
]}

ECKSTEIN, F ^{[1
]}

机构：

[1] MAX PLANCK INST EXPTL MED,CHEM ABT,HERMANN REIN STR 3,W-3400 GOTTINGEN,GERMANY

来源：

NUCLEOSIDES & NUCLEOTIDES | 1992年 / 11卷 / 07期

关键词：

D O I：

10.1080/07328319208021177

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel synthesis of 2'-fluoro-2'-deoxyguanosine employing DAST as the fluorinating agent is presented. The preparation of its phosphoramidite as well as that of 2'-amino-2'-deoxyguanosine is also described.

引用

页码：1333 / 1351

页数：19

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