SITE OF ACTION OF IMPRINTED GENES REVEALED BY PHENOTYPIC ANALYSIS OF PARTHENOGENETIC EMBRYOS

被引：25

作者：

VARMUZA, S

MANN, M

ROGERS, I

机构：

[1] Department of Zoology, University of Toronto, Toronto, Ontario

来源：

DEVELOPMENTAL GENETICS | 1993年 / 14卷 / 03期

关键词：

PARTHENOGENESIS; IMPRINTING; MOUSE DEVELOPMENT;

D O I：

10.1002/dvg.1020140310

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The phenotypes of early postimplantation parthenogenetic embryos were examined. The spectrum of phenotypes suggested that three stages are adversely affected by imprinting-implantation, pregastrulation, and postgastrulation. Survival of parthenogenetic embryos past these developmental blocks can be improved but not completely overcome by experimental asynchrony. These results suggest that imprinting may be ''leaky'' at early stages.

引用

页码：239 / 248

页数：10

共 34 条

[1]

BALAKIER H, 1976, J EMBRYOL EXP MORPH, V35, P25

[2] THE MOUSE INSULIN-LIKE GROWTH-FACTOR TYPE-2 RECEPTOR IS IMPRINTED AND CLOSELY LINKED TO THE TME LOCUS [J].