THE IMMUNOLOGY OF MULTIPLE-SCLEROSIS AND ITS ANIMAL-MODEL, EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

被引:115
作者
OWENS, T [1 ]
SRIRAM, S [1 ]
机构
[1] VANDERBILT UNIV, MED CTR, NASHVILLE, TN USA
关键词
D O I
10.1016/S0733-8619(18)30061-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The observation that multiple sclerosis (MS) is an autoimmune disease derives partly from systemic abnormalities of immune function seen in patients with the disease, and also because of similarities with experimental allergic encephalomyelities (EAE). This article describes what is known of the immunologic processes underlying the human and animal diseases, and discusses whether MS is indeed an autoimmune disease, and whether EAE is a good model for MS.
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页码:51 / 73
页数:23
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