CD44 IS EXPRESSED THROUGHOUT PREIMPLANTATION HUMAN EMBRYO DEVELOPMENT

被引：105

作者：

CAMPBELL, S

SWANN, HR

APLIN, JD

SEIF, MW

KIMBER, SJ

ELSTEIN, M

机构：

[1] UNIV S MANCHESTER HOSP, DEPT OBSTET & GYNAECOL, MANCHESTER M20 2LR, LANCS, ENGLAND

[2] UNIV MANCHESTER, SCH BIOL SCI, MANCHESTER M13 9PT, LANCS, ENGLAND

来源：

HUMAN REPRODUCTION | 1995年 / 10卷 / 02期

关键词：

ADHESION MOLECULE; CD44; CUMULUS; EMBRYO; OOCYTE;

D O I：

10.1093/oxfordjournals.humrep.a135955

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The cell surface glycoprotein CD44 has been demonstrated in a variety of cell types in embryonic and adult tissues. We have established that CD44 is present on human oocytes, cumulus cells, early embryos and pre-hatched blastocysts by indirect immunofluorescence. We have also shown that CD44 is present on 8-11 week placental stroma cells, but not on the trophoblast. These findings demonstrate that CD44 is present throughout preimplantation development, and that down-regulation occurs on the embryonic surface after implantation.

引用

收藏

页码：425 / 430

页数：6

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