METABOLISM IN PORIFERA .9. STUDIES ON THE BIOLOGICAL CONVERSION OF CHOLESTEROL INTO 19-NOR-CHOLESTANOL BY THE SPONGE AXINELLA-POLYPOIDES

被引：16

作者：

MINALE, L ^{[1
]}

PERSICO, D ^{[1
]}

SODANO, G ^{[1
]}

机构：

[1] UNIV NAPLES,FAC FARM,I-80134 NAPLES,ITALY

来源：

EXPERIENTIA | 1979年 / 35卷 / 03期

关键词：

D O I：

10.1007/BF01964307

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The conversion of cholesterol into 19-nor-5α-cholestan-3β-ol by the sponge Axinella polypoides involves a partial loss (40%) of the 3α-hydrogen atom; moreover administration to the sponge of [4-14C]cholesterol tritiated at C-4β and C-7 showed that the 4β- and 7-hydrogen atoms are retained in this conversion. A competitive uptake experiment, [4-14C]cholesterol vs. [7-3H2]5α-cholestanol, showed that the sponge utilized exclusively cholesterol for the production of 19-nor-5α-cholestan-3β-ol. © 1978 Birkhäuser Verlag.

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页码：296 / 297

页数：2

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