PSEUDO-CHEDIAK-HIGASHI ANOMALY IN ACUTE MYELOID-LEUKEMIA - ELECTRON MICROSCOPICAL STUDY

被引：11

作者：

EFRATI, P ^{[1
]}

NIR, E ^{[1
]}

KAPLAN, H ^{[1
]}

DVILANSKI, A ^{[1
]}

机构：

[1] BEN GURION UNIV NEGEV,SOROKA MED CTR,BEER SHEVA 84120,ISRAEL

来源：

ACTA HAEMATOLOGICA | 1979年 / 61卷 / 05期

关键词：

AML; Inclusion bodies; Lysosomes; Pseudo-chediak;

D O I：

10.1159/000207670

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2 cases of acute myeloid leukaemia with inclusion bodies are presented. The inclusions were found mainly in the blast cells but could also be encountered in lymphocytes and plasma cells. Cytochemical and ultrastructural studies showed a great resemblance of these inclusions to the ones found in Chediak-Higashi anomaly, i.e., high acid phosphatase activity, varying in size of inclusions from clusters of small granules to huge inclusion, sometimes found in vacuoles, featuring fusion of lysosomes. © 1979 S. Karger AG, Basel.

引用

页码：264 / 271

页数：8

共 22 条

[1] MORPHOLOGY AND CYTOCHEMISTRY OF THE GRANULE-VACUOLE BODY OF LEUKEMIC CELLS [J].

ACKERMAN, GA .

BLOOD, 1957, 12 (05) :443-447

[2] S-COLLIDINE AS A BASIS FOR BUFFERING FIXATIVES [J].

BENNETT, HS ;

LUFT, JH .

JOURNAL OF BIOPHYSICAL AND BIOCHEMICAL CYTOLOGY, 1959, 6 (01) :113-114

[3]

BERREBI A, 1974, NOUV PRESSE MED, V14, P894

[4] UNUSUAL INCLUSIONS OCCURRING IN BLASTS OF 4 PATIENTS WITH ACUTE-LEUKEMIA AND DOWNS-SYNDROME [J].

BRUNNING, RD ;

PARKIN, J ;

DICK, F ;

NESBIT, M .

BLOOD, 1974, 44 (05) :735-741

[5] ELECTRON-MICROSCOPICAL STUDY OF BONE MARROW CELLS IN A CASE OF CHEDIAK-HIGASHI-STEINBRINCK SYNDROME [J].

EFRATI, P ;

DANON, D .

BRITISH JOURNAL OF HAEMATOLOGY, 1968, 15 (02) :173-&

[6] CHEDIAKS ANOMALY OF LEUKOCYTES IN MALIGNANT LYMPHOMA ASSOCIATED WITH LEUKEMIC MANIFESTATIONS - CASE REPORT WITH NECROPSY [J].

EFRATI, P ;

JONAS, W .

BLOOD, 1958, 13 (11) :1063-1073

[7]

FREEMAN A, 1974, BRIT J HAEMATOL, V20, P225

[8]

GARTON G, 1969, SCAND J HAEMATOL, V6, P365

[9]

GORMAN AM, 1976, AM J CLIN PATHOL, V65, P1030

[10]

KARNOVSKY MJ, 1965, J CELL BIOL, V27, P137

← 1 2 3 →