FACTORS OF IMPORTANCE WHEN EVALUATING QUALITY OF LIFE IN CLINICAL-TRIALS

被引：74

作者：

WIKLUND, I

DIMENAS, E

WAHL, M

机构：

[1] AB HASSLE, RES LABS, S-43183 MOLNDAL, SWEDEN

[2] CLIN RES & COMMUN, BASEL, SWITZERLAND

来源：

CONTROLLED CLINICAL TRIALS | 1990年 / 11卷 / 03期

关键词：

duration of follow-up; placebo effect; Quality of life; trial design;

D O I：

10.1016/0197-2456(90)90011-P

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Quality of life (QoL) has during recent years become recognized as an important outcome in clinical trials. But it is not sufficient just to incorporate QoL measures in a trial. Several factors have important repercussions on the results of clinical trials using QoL as an outcome measure. Unless more attention is directed towards factors that may be important when evaluating QoL, the value of including these measurements in clinical trials will be minimized. Important issues pertain to trial design, duration of follow-up, the role of placebo effects, side effects, and confounding variables. © 1990.

引用

页码：169 / 179

页数：11

共 66 条

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