EFFECTS OF POTASSIUM ON VANADATE INHIBITION OF SARCOPLASMIC-RETICULUM CA-2+-ATPASE FROM DOG CARDIAC AND RABBIT SKELETAL-MUSCLE

被引:107
作者
WANG, T
TSAI, LI
SOLARO, RJ
GRASSIDEGENDE, AO
SCHWARTZ, A
机构
[1] Department of Pharmacology and Cell Biophysics, University of Cincinnati, College of Medicine, Cincinnati
关键词
D O I
10.1016/0006-291X(79)90626-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The concentration of vanadate for half maximal inhibition of dog cardiac and rabbit skeletal SR Ca2+-ATPase was approximately 5 μM. Preincubation of the enzyme with vanadate resulted in greater inhibition. Effects of potassium on the inhibition were studied under various conditions. © 1979.
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页码:356 / 361
页数:6
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