A C-13 NMR-SPECTROSCOPY STUDY OF THE STRUCTURE OF N-H PYRAZOLES AND INDAZOLES

被引：89

作者：

LOPEZ, C

CLARAMUNT, RM

TROFIMENKO, S

ELGUERO, J

机构：

[1] UNIV NACL EDUC DISTANCIA, FAC CIENCIAS, DEPT QUIM ORGAN & BIOL, SENDA REY S-N, E-28040 MADRID, SPAIN

[2] DUPONT CO INC, POLYMERS RES & DEV, EXPTL STN, WILMINGTON, DE 19880 USA

[3] CSIC, INST QUIM MED, E-28006 MADRID, SPAIN

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1993年 / 71卷 / 05期

关键词：

D O I：

10.1139/v93-092

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The C-13 chemical shifts and some H-1-C-13 coupling constants of 23 pyrazoles and indazoles are reported and discussed. The spectra were recorded in CDCl3 and in DMSO-d6 solutions and, in several cases, also in the solid state (CP/MAS technique). These data allow us to determine the tautomerism of these compounds in the solid state (usually only one tautomer) and in solution. The position of the tautomeric equilibrium is related to the Hammett sigma(m) value of the 3(5)-substituent.

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页码：678 / 684

页数：7

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