SPECIFIC TROPISM OF JAPANESE ENCEPHALITIS-VIRUS FOR DEVELOPING NEURONS IN PRIMARY RAT-BRAIN CULTURE

被引：42

作者：

KIMURAKURODA, J

ICHIKAWA, M

OGATA, A

NAGASHIMA, K

YASUI, K

机构：

[1] TOKYO METROPOLITAN INST NEUROSCI,DEPT ANAT & EMBRYOL,FUCHU,TOKYO 183,JAPAN

[2] HOKKAIDO UNIV,SCH MED,DEPT PATHOL,SAPPORO,HOKKAIDO 060,JAPAN

来源：

ARCHIVES OF VIROLOGY | 1993年 / 130卷 / 3-4期

关键词：

D O I：

10.1007/BF01309676

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Among all the neural cells in fetal rat brain culture developing neurons showed the highest rate of infection by Japanese encephalitis virus (JEV). JEV specifically bound to these cells as measured by immuno-staining. These results indicate that developing neurons are the major target of JEV, and that the initial specific binding of virus to these cells may be one of the reasons for the neurotropism of JEV.

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收藏

页码：477 / 484

页数：8

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