A PREDICTION OF THE SECONDARY STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN

被引：13

作者：

JENNY, TF ^{[1
]}

BENNER, SA ^{[1
]}

机构：

[1] SWISS FED INST TECHNOL, DEPT CHEM, CH-8092 ZURICH, SWITZERLAND

来源：

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS | 1994年 / 20卷 / 01期

关键词：

PROTEIN SECONDARY STRUCTURE PREDICTION; PLECKSTRIN HOMOLOGY DOMAIN;

D O I：

10.1002/prot.340200102

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A consensus prediction for the secondary structure of the pleckstrin homology (PH) domain is presented. The prediction is based on an analysis of patterns of conservation and variation of homologous protein sequences. The structure is predicted to be formed largely from beta strands with a single alpha helix. (C) 1994 Wiley-Liss, Inc.

引用

页码：1 / 3

页数：3

共 21 条

[1] STRUCTURAL DESIGN AND MOLECULAR EVOLUTION OF A CYTOKINE RECEPTOR SUPERFAMILY [J].

BAZAN, JF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (18) :6934-6938

[2] BONA-FIDE PREDICTION OF ASPECTS OF PROTEIN CONFORMATION - ASSIGNING INTERIOR AND SURFACE RESIDUES FROM PATTERNS OF VARIATION AND CONSERVATION IN HOMOLOGOUS PROTEIN SEQUENCES [J].

BENNER, SA ;

BADCOE, I ;

COHEN, MA ;

GERLOFF, DL .

JOURNAL OF MOLECULAR BIOLOGY, 1994, 235 (03) :926-958

[3] PREDICTED SECONDARY STRUCTURE FOR THE SRC HOMOLOGY-3 DOMAIN [J].

BENNER, SA ;

COHEN, MA ;

GERLOFF, D .

JOURNAL OF MOLECULAR BIOLOGY, 1993, 229 (02) :295-305

[4] PATTERNS OF DIVERGENCE IN HOMOLOGOUS PROTEINS AS INDICATORS OF SECONDARY AND TERTIARY STRUCTURE - A PREDICTION OF THE STRUCTURE OF THE CATALYTIC DOMAIN OF PROTEIN-KINASES [J].

BENNER, SA ;

GERLOFF, D .

ADVANCES IN ENZYME REGULATION, 1991, 31 :121-181

[5]

BENNER SA, 1989, ADV ENZYME REGUL, V28, P219, DOI 10.1016/0065-2571(89)90073-3

[6] PREDICTING THE CONFORMATION OF PROTEINS - MAN VERSUS MACHINE [J].

BENNER, SA ;

GERLOFF, DL .

FEBS LETTERS, 1993, 325 (1-2) :29-33

[7]

BENNER SA, IN PRESS J MOL RECOG

[8]

BENNER SA, 1992, CURR OPIN STRUC BIOL, V2, P402

[9] PREDICTION OF SECONDARY STRUCTURE BY EVOLUTIONARY COMPARISON - APPLICATION TO THE ALPHA-SUBUNIT OF TRYPTOPHAN SYNTHASE [J].

CRAWFORD, IP ;

NIERMANN, T ;

KIRSCHNER, K .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1987, 2 (02) :118-129

[10] A SECONDARY STRUCTURE PREDICTION OF THE HEMORRHAGIC METALLOPROTEASE FAMILY [J].

GERLOFF, DL ;

JENNY, TF ;

KNECHT, LJ ;

BENNER, SA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 194 (01) :560-565

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