SUCCESSFUL OUTCOME OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY WITH CYTARABINE AND INTERFERON

被引：58

作者：

STEIGER, MJ

TARNESBY, G

GABE, S

MCLAUGHLIN, J

SCHAPIRA, AHV

机构：

[1] ROYAL FREE HOSP,DEPT NEUROSCI,LONDON,ENGLAND

[2] ROYAL FREE HOSP,DEPT PATHOL,LONDON,ENGLAND

来源：

ANNALS OF NEUROLOGY | 1993年 / 33卷 / 04期

关键词：

D O I：

10.1002/ana.410330415

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The prognosis of patients with progressive multifocal leukoencephalopathy is poor, with few patients showing remission or surviving. We describe a 37-year-old man who developed progressive multifocal leukoencephalopathy in association with sarcoidosis. Despite treatment with cytarabine and acyclovir, he continued to deteriorate. Shortly following the addition of interferon alfa, he made a dramatic improvement, regaining full functional independence. The use of interferon alfa in addition to cytarabine in such patients offers a new therapeutic approach worthy of further trial.

引用

页码：407 / 411

页数：5

共 15 条

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