REGULATION OF CYCLIC-AMP IN HEART AND GILL OF APLYSIA BY THE PUTATIVE NEUROTRANSMITTERS DOPAMINE AND SEROTONIN

被引:31
作者
KEBABIAN, PR [1 ]
KEBABIAN, JW [1 ]
CARPENTER, DO [1 ]
机构
[1] NINCDS, BETHESDA, MD 20014 USA
关键词
D O I
10.1016/0024-3205(79)90064-X
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Serotonin (5-HT) and dopamine (DA), but not several other putative neurotransmitters, stimulate cyclic adenosine-3',5'-monophosphate (cAMP) production in slices of Aplysia gill. Furthermore, 5-HT but not DA increases cAMP in slices of the heart of Aplysia. Several lines of evidence indicate that the receptors are distinct entities; however, no drugs were found to block one receptor without affecting the other. © 1979.
引用
收藏
页码:1757 / 1764
页数:8
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