NUCLEAR RESONANT SCATTERING OF GAMMA-RAYS - NEW TECHNIQUE FOR INVIVO MEASUREMENT OF BODY IRON STORES

被引:26
作者
VARTSKY, D
ELLIS, KJ
HULL, DM
COHN, SH
机构
[1] Medical Research Center, Brookhaven National Laboratory, Upton, NY
关键词
D O I
10.1088/0031-9155/24/4/001
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A technique for the measurement of body iron utilising nuclear resonant scattering of gamma rays has been developed. 847 keV photons emitted from a gaseous 56MnCl2 source are resonantly scattered from 56Fe present in the body. Measurement is made using large volume Ge(Li) detectors. The spatial uniformity of activation, the sensitivity of the detection system and the limits of detection have been investigated. Measurements were made on a liver phantom. The resonance scattering technique permits determination of normal levels of Fe in the liver with a radiation dose of 2 rem.
引用
收藏
页码:689 / 701
页数:13
相关论文
共 26 条
[1]  
ALTIKRITY SA, 1976, THESIS U BIRMINGHAM
[2]   LONG-TERM CHELATION THERAPY IN THALASSEMIA MAJOR - EFFECT ON LIVER IRON CONCENTRATION, LIVER HISTOLOGY, AND CLINICAL PROGRESS [J].
BARRY, M ;
FLYNN, DM ;
LETSKY, EA ;
RISDON, RA .
BMJ-BRITISH MEDICAL JOURNAL, 1974, 2 (5909) :16-20
[3]  
BEGZHANOV RB, 1963, SOV PHYS JETP-USSR, V17, P94
[4]   IRON IN HEART - ETIOLOGY AND CLINICAL SIGNIFICANCE [J].
BUJA, LM ;
ROBERTS, WC .
AMERICAN JOURNAL OF MEDICINE, 1971, 51 (02) :209-&
[5]  
ELLIS JT, 1954, AM J PATHOL, V30, P287
[6]  
ENGLE MA, 1964, ANN NY ACAD SCI, V119, P694
[7]   IDIOPATHIC HEMOCHROMATOSIS, AN IRON STORAGE DISEASE .A. IRON METABOLISM IN HEMOCHROMATOSIS [J].
FINCH, SC ;
FINCH, CA .
MEDICINE, 1955, 34 (04) :381-430
[8]  
HARKER LA, 1968, AM J MED, V45, P108
[9]   BETA SPECTRUM OF MN56 [J].
HOWE, DA ;
WORTMAN, DE ;
LANGER, LM ;
SPEJEWSKI, EH .
PHYSICAL REVIEW, 1962, 128 (06) :2748-+
[10]   RESONANT SCATTERING OF GAMMA-RAYS IN CU-63 AND FE-56 [J].
ILAKOVAC, K .
PROCEEDINGS OF THE PHYSICAL SOCIETY OF LONDON SECTION A, 1954, 67 (415) :601-607