RECOMBINANT FOWLPOX VIRUSES INDUCING PROTECTIVE IMMUNITY AGAINST NEWCASTLE-DISEASE AND FOWLPOX VIRUSES

被引：38

作者：

OGAWA, R

YANAGIDA, N

SAEKI, S

SAITO, S

OHKAWA, S

GOTOH, H

KODAMA, K

KAMOGAWA, K

SAWAGUCHI, K

IRITANI, Y

机构：

[1] NIPPON ZEON CO LTD,CTR RES & DEV,INST BIOL SCI,1-2-1 YAKO,KAWASAKI KU,KAWASAKI 210,JAPAN

[2] SHIONOGI & CO LTD,ABURAHI LABS,KOKA,SHIGA 53034,JAPAN

来源：

VACCINE | 1990年 / 8卷 / 05期

关键词：

fowlpox; Newcastle disease; recombinant DNA;

D O I：

10.1016/0264-410X(90)90251-G

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The haemagglutinin-neuraminidase gene of Newcastle disease virus was inserted into a non-essential region of the fowlpox virus genome and expressed under control of the vaccinia virus 7.5 kDa polypeptide gene promoter. Immunization with the recombinant fowlpox virus elicited protective immunity in chickens against both virulent Newcastle disease and fowlpox virus infection. © 1990.

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收藏

页码：486 / 490

页数：5

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