PRODUCTION OF TYPE-1 FIMBRIAE BY ESCHERICHIA-COLI HB101

被引：13

作者：

ELLIOTT, SJ

NANDAPALAN, N

CHANG, BJ

机构：

[1] UNIV WESTERN AUSTRALIA, DEPT MICROBIOL, NEDLANDS, WA 6009, AUSTRALIA

[2] QUEEN ELIZABETH II MED CTR, NEDLANDS, WA 6009, AUSTRALIA

来源：

MICROBIAL PATHOGENESIS | 1991年 / 10卷 / 06期

基金：

英国医学研究理事会;

关键词：

ESCHERICHIA-COLI; TYPE-1; FIMBRIAE; HEMAGGLUTINATION; ADHESION; CLONING; VIRULENCE GENES;

D O I：

10.1016/0882-4010(91)90114-P

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Escherichia coli HB101 is frequently used as a host in the cloning of bacterial virulence genes because of its reported lack of virulence determinants such as fimbriae, adhesins and haemagglutinins. However, passage of HB101 in standing broth culture rapidly induced the production of fimbriae which mediated adhesion to HEp-2 cells and mannose-sensitive haemagglutination of human and guinea-pig erythrocytes. Fimbrial serology, morphology and pilin molecular mass of 18 kDa were consistent with those of type 1 fimbriae. © 1991.

引用

页码：481 / 486

页数：6

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