SERUM IRON AND RISK OF FATAL ACUTE MYOCARDIAL-INFARCTION

被引:134
作者
MORRISON, HI
SEMENCIW, RM
MAO, Y
WIGLE, DT
机构
[1] Bureau of Chronic Disease Epidemiology, Health and Welfare Canada, Ottawa, ON
关键词
MYOCARDIAL INFARCTION; IRON; TRANSFERRIN; HEMOGLOBIN; CORONARY HEART DISEASE; CHOLESTEROL LEVELS; GENDER; POPULATION SURVEY;
D O I
10.1097/00001648-199403000-00015
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We assessed the relation of serum iron, dietary iron, and the use of iron supplements to the risk of fatal acute myocardial infarction in the Nutrition Canada Survey cohort. We found an association between serum iron and risk of fatal acute myocardial infarction, with rare ratios for males and females in the highest category of serum iron (greater than or equal to 175 mu g per dl):of 2.18 [95% confidence intervals (CI) = 1.01-4.74] and 5.53 (95% CI = 1.69-18.12), respectively. We found no important association between risk of fatal acute myocardial infarction and either dietary iron or iron supplement use among the 9,920 participants included in this study.
引用
收藏
页码:243 / 246
页数:4
相关论文
共 15 条
  • [1] Semenciw R., Morrison H., Mao Y., Johansen H., Davies J.W., Wigle D., Major risk factors for cardiovascular disease mortality in adults: Results from the Nutrition Canada Survey, Int J Epidemiol, 17, pp. 317-324, (1988)
  • [2] Kannel B., An overview of the risk factors for cardiovascular disease, Prevention of Coronary Heart Disease, pp. 1-19, (1983)
  • [3] Martin M., Browner W.S., Wentworth D., Hulley S.B., Kuller L.H., Serum cholesterol, blood pressure, and mortality: Implications from a cohort of 361,662 men, Lancet, 2, pp. 923-926, (1986)
  • [4] Salonen J.T., Nyyssonen K., Korpela H., Tuomilehto J., Seppanen R., Salonen R., High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men, Circulation, 86, pp. 803-811, (1992)
  • [5] Rimm E.B., Stampfer M.J., Ascherio A., Giovannucci E., Colditz G.A., Willett W.C., Vitamin E consumption and the risk of coronary heart disease in men, N Engl J Med, 328, pp. 1450-1456, (1993)
  • [6] Stampfer M.J., Hennekens C.H., Manson J.E., Colditz G.A., Rosner B., Willett W.C., Vitamin E consumption and the risk of coronary heart disease in women, N Engl J Med, 328, pp. 1444-1449, (1993)
  • [7] Nutrition Canada National Survey, (1973)
  • [8] Johansen H., Semenciw R., Morrison H.I., Mao Y., Verdier P., Smith M.E., Wigle D.T., Important risk factors for adult mortality: A ten year follow-up of the Nutrition Canada survey cohort, Can Med Assoc J, 136, pp. 823-828, (1987)
  • [9] Nutrition Canada Food Consumption Patterns Report, (1973)
  • [10] Howe G., Lindsay J., A generalized iterative record linkage computer system for use in medical follow-up studies, Comput Biomed Res, 14, pp. 327-340, (1981)