A NEW SCALARANE SESTERTERPENOID FROM THE MARINE SPONGE CACOSPONGIA MOLLIOR

被引：41

作者：

DEROSA, S ^{[1
]}

PULITI, R ^{[1
]}

CRISPINO, A ^{[1
]}

DEGIULIO, A ^{[1
]}

MATTIA, CA ^{[1
]}

MAZZARELLA, L ^{[1
]}

机构：

[1] UNIV NAPLES,DIPARTIMENTO CHIM,I-80134 NAPLES,ITALY

来源：

JOURNAL OF NATURAL PRODUCTS | 1994年 / 57卷 / 02期

关键词：

D O I：

10.1021/np50104a010

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new sesterterpene, 12-deacetoxyscalaradial [2a] has been isolated from the sponge Cacospongia mollior, together with the previously described scalaradial [2b] and furoscalarol [3]. The structure of the new compound, proposed by spectral data, was confirmed by X-ray diffraction analysis. Compound 2a is the first scalarane sesterterpenoid, without a substituent at C-12, to have been identified in nature. It shows high antifeedant activity and is hot to taste for the human tongue. Both 2a and 2b display cytotoxic activity.

引用

页码：256 / 262

页数：7

共 17 条

[1]

CAFIERI F, 1977, GAZZ CHIM ITAL, V107, P71

[2] INSECT ANTIFEEDANT ACTIVITY AND HOT TASTE FOR HUMANS OF SELECTED NATURAL AND SYNTHETIC 1,4-DIALDEHYDES [J].