A TOTAL SYNTHESIS OF (+)-EREMANTHOLIDE-A

被引：20

作者：

TAKAO, K ^{[1
]}

OCHIAI, H ^{[1
]}

HASHIZUKA, T ^{[1
]}

KOSHIMURA, H ^{[1
]}

TADANO, K ^{[1
]}

OGAWA, S ^{[1
]}

机构：

[1] KEIO UNIV,DEPT APPL CHEM,KOHOKU KU,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 09期

关键词：

D O I：

10.1016/0040-4039(95)00066-L

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereoselective and enantiospecific total synthesis of (+)-eremantholide A (1) is described. The present total synthesis features 1) regio- and stereoselective radical carbocyclization of D-glurose-derived gamma-lactone 7, and 2) a nine-membered ring formation by the coupling reaction of bicyclic triflate 18 and known furanone 19 followed by a vinylogous aldol reaction.

引用

页码：1487 / 1490

页数：4

共 13 条

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