PARACETAMOL-INDUCED FIXED DRUG ERUPTION WITH POSITIVE IMMUNOFLUORESCENCE FINDINGS

被引：4

作者：

DUHRA, P

PORTER, DI

机构：

[1] Skin Department, Coventry and Warwickshire Hospital, Coventry, CV1 4FH, Stoney Stanton Road

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 1990年 / 15卷 / 04期

关键词：

D O I：

10.1111/j.1365-2230.1990.tb02093.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A 93‐year‐old woman with an 8‐year history of episodes of fixed drug eruption due to paracetamol is described. The rash was characterized by bullae, crusted lesions, hyperpigmented and erythematous patches as well as lesions resembling toxic epidermal necrolysis. Direct immunofluorescence revealed deposition of IgG and C3 in the epidermal intercellular cement substance of lesional skin only; the pathogenetic significance of this finding is discussed. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：293 / 295

页数：3

共 9 条

[1]

GUIN JD, 1988, CUTIS, V41, P106

[2] WANDERING FIXED DRUG ERUPTION - A MUCOCUTANEOUS REACTION TO ACETAMINOPHEN [J].