PROGESTERONE BIOCONVERSION BY MICROALGAL CULTURES

被引：36

作者：

POLLIO, A

PINTO, G

DELLAGRECA, M

DEMAIO, A

FIORENTINO, A

PREVITERA, L

机构：

[1] UNIV NAPLES FEDERICO II,DIPARTIMENTO CHIM ORGAN & BIOL,I-80134 NAPLES,ITALY

[2] UNIV NAPLES FEDERICO II,DIPARTIMENTO BIOL VEGETALE,I-80139 NAPLES,ITALY

来源：

PHYTOCHEMISTRY | 1994年 / 37卷 / 05期

关键词：

MICROALGAL SUSPENSION CULTURE; PROGESTERONE; BIOTRANSFORMATION; 3-HYDROXY-9,10-SECO-PREGNA-1,3,5(10)-TRIENE-9,20-DIONE;

D O I：

10.1016/S0031-9422(00)90396-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ten different strains of unicellular microalgae have been used in the bioconversion of progesterone. Regio and stereoselective reduction and hydroxylation of the title compound were induced. A 9,10-seco derivative was obtained in high yield by using Scenedesmus quadricauda.

引用

页码：1269 / 1272

页数：4

共 14 条

[1]

ABDULHAJJ YJ, 1986, J NAT PRODUCTS, V49, P244

[2] C-13 NMR-STUDIES .69. C-13 NMR-SPECTRA OF STEROIDS - SURVEY AND COMMENTARY [J].