HIGHLY OXYGENATED QUASSINOIDS FROM EURYCOMA-LONGIFOLIA

被引：45

作者：

MORITA, H

KISHI, E

TAKEYA, K

ITOKAWA, H

IITAKA, Y

机构：

[1] TOKYO COLL PHARM, DEPT PHARMACOGNOSY, 1432-1 HORINOUCHI, HACHIOJI, TOKYO 19203, JAPAN

[2] TEIKYO UNIV, FAC MED, HACHIOJI, TOKYO 19203, JAPAN

来源：

PHYTOCHEMISTRY | 1993年 / 33卷 / 03期

关键词：

EURYCOMA-LONGIFOLIA; SIMAROUBACEAE; QUASSINOID; CYTOTOXICITY;

D O I：

10.1016/0031-9422(93)85475-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two novel C19-skeleton quassinoids, one with a lactonic linkage at C-7 and another with a lactonic linkage at C-12, and seven novel highly oxygenated quassinoids with a C20-skeleton were isolated from the leaves of Eurycoma longifolia. Their structures and stereochemistry were established by spectroscopic data, including two-dimensional NMR techniques, and X-ray analysis. The relationships between their structures and cytotoxicities are also discussed.

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收藏

页码：691 / 696

页数：6

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