Isolated spectrin covalently attached to a surface in a liquid environment as well as dried on mica has been studied with a contact-mode atomic force microscope. Both pyramidal and conical-type cantilever tip facets were used in the AFM. Our images show structures and give dimensions that correlate well with previous structural studies using transmission electron microscopy.
机构:
Duke Univ, Med Ctr, Howard Hughes Med Inst, Durham, NC 27710 USA
Duke Univ, Med Ctr, Dept Biochem, Durham, NC 27710 USADuke Univ, Med Ctr, Howard Hughes Med Inst, Durham, NC 27710 USA
机构:
Duke Univ, Med Ctr, Howard Hughes Med Inst, Durham, NC 27710 USA
Duke Univ, Med Ctr, Dept Biochem, Durham, NC 27710 USADuke Univ, Med Ctr, Howard Hughes Med Inst, Durham, NC 27710 USA