HYPOTHALAMIC HORMONES - FROM NEUROENDOCRINOLOGY TO CANCER-THERAPY

被引:52
作者
SCHALLY, AV [1 ]
机构
[1] TULANE UNIV, SCH MED, DEPT MED, EXPTL MED SECT, NEW ORLEANS, LA 70112 USA
关键词
ANTITUMOR ACTIVITY; BOMBESIN GASTRIN RELEASING PEPTIDE; CORTICOTROPIN-RELEASING FACTOR; CYTOTOXIC PEPTIDE ANALOGS; LUTEINIZING HORMONE-RELEASING HORMONE; SOMATOSTATIN;
D O I
10.1097/00001813-199404000-00001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The discovery of hypothalamic hormones, especially LH-RH and somatostatin has led to practical clinical use of their analogs in the field of cancer treatment. Bombesin/ GRP antagonists can be also considered for the development of new methods for treatment of various tumors. The understanding of functions of these peptide hormones and the availability of their synthetic analogs should permit the clinicians to treat a variety of cancers more successfully than in the past.
引用
收藏
页码:115 / 130
页数:16
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