EFFECTS OF D-AMPHETAMINE ON THE RECOVERY OF FUNCTION FOLLOWING CEREBRAL ISCHEMIC-INJURY

被引：11

作者：

COLBOURNE, F

CORBETT, D

机构：

[1] Division of Basic Medical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1992年 / 42卷 / 04期

关键词：

ISCHEMIA; DIASCHISIS; RECOVERY OF FUNCTION; AMPHETAMINE;

D O I：

10.1016/0091-3057(92)90018-B

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Amphetamine with appropriate motor experience has been found to facilitate the recovery of motor function after several different types of brain injuries. We investigated whether amphetamine would hasten the recovery of spatial mapping ability in gerbils previously subjected to a 3-min episode of forebrain ischemia. Amphetamine did not promote behavioral recovery, nor did it attenuate ischemic cell damage of hippocampal CA1 neurons. The beneficial effects of amphetamine after brain injury may be limited to restoration of sensorimotor ability and not to cognitive functions such as memory.

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收藏

页码：705 / 710

页数：6

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