COMPARISON OF ENTEROTOXIN PRODUCTION, CYTOTOXIN PRODUCTION, SEROGROUPING, AND ANTIMICROBIAL SUSCEPTIBILITIES OF CLOSTRIDIUM-DIFFICILE STRAINS ISOLATED FROM AIDS AND HUMAN IMMUNODEFICIENCY VIRUS-NEGATIVE PATIENTS

被引：22

作者：

BARBUT, F

DEPITRE, C

DELMEE, M

CORTHIER, G

PETIT, JC

机构：

[1] INRA,UNITE ECOL & PHYSIOL SYST DIGESTIF FONCT BACTERIES INTESTINALES,F-78350 JOUY EN JOSAS,FRANCE

[2] UNIV CATHOLIQUE LOUVAIN,MICROBIOL UNIT,B-1200 BRUSSELS,BELGIUM

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1993年 / 31卷 / 03期

关键词：

D O I：

10.1128/JCM.31.3.740-742.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We analyzed and compared Clostridium difficile strains isolated from diarrheic stools of 49 human immunodeficiency virus (HIV)-negative and 50 AIDS patients. Our results suggest that distribution patterns of serogroups are different in these two populations. Serogroup C (which has been previously reported to be very resistant to antimicrobial agents) represents 66.0 and 18.4% of the isolates from AIDS and HIV-negative patients, respectively (P < 0.001); the selection of serogroup C could be explained by multiple antibiotic pressure to which AIDS patients have been subjected.

引用

页码：740 / 742

页数：3

共 11 条

[1] PROTECTION AGAINST EXPERIMENTAL PSEUDOMEMBRANOUS COLITIS IN GNOTOBIOTIC MICE BY USE OF MONOCLONAL-ANTIBODIES AGAINST CLOSTRIDIUM-DIFFICILE TOXIN-A [J].