RECIPROCAL INTERACTIONS IN DESATURATION OF LINOLEIC ACID INTO GAMMA-LINOLENIC AND EICOSA-8,11,14-TRIENOIC INTO ARACHIDONIC

被引:31
作者
BRENNER, RR
机构
[1] Catedra de Bioquimica Instituto de Fisiologia, Facultad de Ciencias Medicas, La Plata
关键词
D O I
10.1007/BF02531052
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Variable concentrations of [I14C] linoleic acid and [I14C] eicosa-8,11,14-trienoic acid were incubated with liver microsomes in a medium containing the necessary cofactors for fatty acid desaturation. The conversion of linoleic into γ-linolenic acid and eicosatrienoic into arachidonic acid were mutually inhibited and the inhibition depended on the concentration of the fatty acids incubated. © 1969 The American Oil Chemists' Society.
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页码:621 / &
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