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DRUG TARGETING IN CANCER-CHEMOTHERAPY - A CLINICAL PERSPECTIVE

被引：67
作者：
GUPTA, PK [1 ]
机构：
[1] UNIV KENTUCKY,COLL PHARM,LEXINGTON,KY 40536
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 1990年 / 79卷 / 11期
关键词：
D O I：
10.1002/jps.2600791102
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Drug targeting is a phenomenon which maneuvers the distribution of drug in the body in such a manner that the major fraction of the drug interacts exclusively with the target tissue at a cellular or subcellular level. Numerous strategies have been developed to accomplish this goal; some of them have been tried clinically for improving cancer chemotherapy. This review updates the current status of research in the area of targeted drug delivery, with particular emphasis on its application in the clinical management of carcinomas. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company
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页码：949 / 962
页数：14
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