CARBONYL HYDRATION OF OXYMORPHONE AND OXYCODONE HYDROCHLORIDE

被引：3

作者：

CALDWELL, GW

GAUTHIER, AD

VILLANI, FJ

MARYANOFF, CA

LEO, G

机构：

[1] The R.W. Johnson Pharmaceutical Research Institute at McNeil Pharmaceutical Spring house

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 31期

关键词：

D O I：

10.1016/S0040-4039(00)79370-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The minor component observed in aqueous proton (H-1) and carbon (C-13) NMR spectra of oxymorphone HCl and oxycodone HCl is produced by the reaction of these salts with water forming gem-diols and not due to the axial N-methyl isomer.

引用

页码：3763 / 3766

页数：4

共 11 条

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