AQUEOUS-HUMOR CONCENTRATION OF THE QUINOLONE NORFLOXACIN FOLLOWING LOCAL-ADMINISTRATION

被引:7
作者
BEHRENSBAUMANN, W
机构
关键词
QUINOLONES; AQUEOUS HUMOR CONCENTRATION; TOPICAL APPLICATION; NORFLOXACIN;
D O I
10.1159/000310204
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
The Aqueous humor concentration of norfloxacin was measured following topical administration in 20 eyes. The substance was applied at different time intervals. Nineteen samples obtained prior to cataract extraction had mean concentrations between 0.014 and 0.105-mu-g/ml. These concentrations are under the MIC90 of most germs. One eye with minimal congestion due to a neovascular glaucoma, however, had a concentration of 0.206-mu-g/ml.
引用
收藏
页码:213 / 216
页数:4
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