STRUCTURE ACTIVITY RELATIONSHIPS AMONG METHOCTRAMINE-RELATED POLYMETHYLENE TETRAAMINES - CHAIN-LENGTH AND SUBSTITUENT EFFECTS ON M-2 MUSCARINIC RECEPTOR BLOCKING ACTIVITY

被引：38

作者：

MELCHIORRE, C

QUAGLIA, W

PICCHIO, MT

GIARDINA, D

BRASILI, L

ANGELI, P

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 01期

关键词：

D O I：

10.1021/jm00121a017

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：79 / 84

页数：6

共 34 条

[1] THE CARDIOSELECTIVITY OF HIMBACINE - A MUSCARINE RECEPTOR ANTAGONIST [J].

ANWARUL, S ;

GILANI, H ;

COBBIN, LB .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1986, 332 (01) :16-20

[2] SOME QUANTITATIVE USES OF DRUG ANTAGONISTS [J].

ARUNLAKSHANA, O ;

SCHILD, HO .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1959, 14 (01) :48-58

[3] AN APPROXIMATE DESCRIPTION OF THE PI-ELECTRON DISTRIBUTION IN PYRIDINE, FURAN, AND PYRROLE AS CORRELATED WITH THE MOLECULAR MODEL, THE DIPOLE MOMENT AND THE CHEMICAL PROPERTIES OF THESE COMPOUNDS [J].

BAK, B .

ACTA CHEMICA SCANDINAVICA, 1955, 9 (08) :1355-1361

[4] A SEARCH FOR SELECTIVE ANTAGONISTS AT M2-MUSCARINIC RECEPTORS [J].

BARLOW, RB ;

SHEPHERD, MK .

BRITISH JOURNAL OF PHARMACOLOGY, 1985, 85 (02) :427-435

[5] COMPARISON OF AFFINITY CONSTANTS FOR MUSCARINE-SENSITIVE ACETYLCHOLINE RECEPTORS IN GUINEA-PIG ATRIAL PACEMAKER CELLS AT 29 DEGREESC AND IN ILEUM AT 29 DEGREESC AND 37 DEGREESC [J].

BARLOW, RB ;

BERRY, KJ ;

GLENTON, PAM ;

NIKOLAOU, NM ;

SOH, KS .

BRITISH JOURNAL OF PHARMACOLOGY, 1976, 58 (04) :613-620

[6] THE ACTIONS OF SOME ESTERS OF 4-HYDROXYQUINUCLIDINE ON GUINEA-PIG ILEUM, ATRIA AND RAT FUNDUS STRIP [J].

BARLOW, RB ;

KITCHEN, R .

BRITISH JOURNAL OF PHARMACOLOGY, 1982, 77 (03) :549-557

[7] IRREVERSIBLE ALPHA-ADRENOCEPTOR BLOCKING EFFECTS AND REVERSIBLE MUSCARINIC BLOCKING AND NICOTINIC BLOCKING EFFECTS OF TETRAMINE DISULFIDES ON THE HEART [J].

BENFEY, BG ;

BELLEAU, B ;

BRASILI, L ;

GIANNELLA, M ;

MELCHIORRE, C .

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1980, 58 (12) :1477-1483

[8] IDENTIFICATION OF A FAMILY OF MUSCARINIC ACETYLCHOLINE-RECEPTOR GENES [J].

BONNER, TI ;

BUCKLEY, NJ ;

YOUNG, AC ;

BRANN, MR .

SCIENCE, 1987, 237 (4814) :527-532

[9]

DEVINSKY F, 1980, SYNTHESIS-STUTTGART, P303

[10] CARDIOSELECTIVE PROFILE OF AF-DX-116, A MUSCARINE M2 RECEPTOR ANTAGONIST [J].

GIACHETTI, A ;

MICHELETTI, R ;

MONTAGNA, E .

LIFE SCIENCES, 1986, 38 (18) :1663-1672

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