TOTAL SYNTHESIS OF (+)-PREUSSIN, A NOVEL ANTIFUNGAL AGENT

被引：56

作者：

PAK, CS

LEE, GH

机构：

[1] Korea Research Institute of Chemical Technology, Daedeog-Danji, Chungnam

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 03期

关键词：

D O I：

10.1021/jo00003a040

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of (+)-preussin, (2S,3S,5R)-1-methyl-5-nonyl-2-(phenylmethyl)-3-pyrrolidinol, was achieved by using D-glucose as the starting material. The key synthetic steps involved the sequential reduction and cyclization of azido triflate 6 to construct the pyrrolidine moiety 7 with the proper stereochemistry.

引用

页码：1128 / 1133

页数：6

共 29 条

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